Cancer cell experiencing endoplasmic reticulum stress. Credit: Ella Marushchenko (2018)
According to a study led by researchers at Weill Cornell Medicinea protein prevalent in high quantities within lung cancer cells has been found to regulate a critical immunosuppressive pathway, enabling lung tumors to avoid immune response. This discovery could accelerate the creation of treatments aimed at overcoming this tumor defense mechanism, ultimately enhancing the prospects for lung cancer patients.
The researchers, in their study published in the journal DOI: 10.1038/s41467-022-35584-9
Dr. Juan Cubillos-Ruiz is a scientific consultant for NextRNA Therapeutics and Autoimmunity Biologic Solutions, and holds patents on IRE1α modulation for the treatment of disease.
