The new finding could pave the way for new effective treatments for the coronavirus.
They discovered that the organic compound can bind to many SARS-CoV-2 proteins.
Researchers have discovered that salen can effectively bind a number of proteins of the coronavirus Ural Federal University.
According to scientists, salen – the substance in the photo – is relatively simple and inexpensive to synthesize. Credit: Ural Federal University / Damir Safin
The term “salen” refers to a tetradentate Schiff base derived from salicylaldehyde and ethylenediamine. Salen and its derivatives are key ligands in a wide range of practical applications. This is an organic substance that has the ability to coordinate certain metals and keep them stable in various oxidation states. Metal complex compounds of salen derivatives are also used as catalysts.
Two “fluid” hydrogen atoms of hydroxyl groups are found in salen. Each of these hydrogen atoms has the ability to move to a nitrogen DOI: 10.1080/10406638.2022.2097281
A study was carried out by scientists from the Innovation Center of Chemical and Pharmaceutical Technologies of Ural Federal University, Kurgan State University, and Tyumen State University.
