Researchers at Cedars-Sinai have conducted the most comprehensive analysis of retinal changes in Alzheimer’s disease patients and their correlation with brain and cognitive changes. Published in the journal Acta Neuropathologica, this study is crucial for understanding the intricate effects of Alzheimer’s on the retina, particularly in the early stages of cognitive impairment. This understanding is vital for developing more effective treatments to halt the disease’s progression.
Cedars-Sinai Investigators Map Changes to the Retina That Correspond to Brain Changes in the Early Stage, Opening a Path to Earlier Diagnosis
An analysis led by Cedars-Sinai investigators is an important step toward understanding the complex effects of DOI: 10.1007/s00401-023-02548-2
Funding: This work was supported by the National Institutes of Health (NIH) National Institute on Aging grant numbers R01AG056478, R01AG055865, AG056478-04S1, and R01AG062007; NIH National Institute of General Medical Sciences grant number R01 GM132129; NIH National Eye Institute grant number R01EY013431; the Haim Saban, Maurice Marciano, and Tom Gordon private foundations; Australian National Health and Medical Research Council grant numbers GNT1128436, GNT1129192, and GNT1139469; the Clem Jones Centre for Ageing Dementia Research; the National Health and Medical Research Council; the Petersen Foundation; the Australian Government’s National Collaborative Research Infrastructure Scheme; Fondo Ordinario Enti of Italian CNR; and Macquarie University.
